This theme is focused on developing a digital manufacturing platform to deliver reductions in manufacturing times for pharmaceutical production. This will be delivered by construction of an agile, evolving, manufacturing platform technology based around additive manufacturing and machine learning, incorporating design optimisation, modelling, sensing, and materials development.

Early studies have focused on:

• Improving an existing virus inactivation stage from a GSK biopharmaceutical manufacturing process. This has resulted in GSK bringing new colleagues into the Partnership providing additional expertise in these key areas.

• Direct on-site engagement of researchers from this theme within GSK facilities has enabled an understanding of existing processes.

Britest-facilitated workshops have allowed the wider project team to gain a deeper understanding of the virus inactivation process, with the outputs now driving the research endeavours within this theme.

People

Prof Alastair Florence (UoS)
Dr Cameron Brown (UoS)
Dr Blair Johnston (UoS)
Prof Ricky Wildman (UoN)
Prof Derek Irvine (UoN)
Prof Clive Roberts (UoN)
Dr Anna Croft (UoN)
Dr Ender Özcan (UoN)
Dr Laurent Strodiot (GSK)
Dr Gareth Alford (GSK)
Martin Wallace (GSK)
Dr Jason Hutchinson (PDRA, UoN)
Dr Simeng Wang (PDRA, UoN)
Dr Aleksandr Josifovic (PDRA, UoS)
Dr Cecilia Barrera (PDRA, UoS)