This theme is focused on the delivery of new and efficient processes that will be directly applicable to the production of drug-like molecules. Importantly, a key design principle formulated in partnership with GSK is that these new approaches should be broadly applicable in both medicinal chemistry and process development scenarios.
Achievements to date include:<\/p>\n\n\n\n
\u2022 The N<\/em>-methyl functionalisation synthetic programme is developing rapidly in partnership with mechanistic investigations in our Sustainable Processes theme.<\/p>\n\n\n\n
\u2022 The first generation of a novel class of ligands to enable the asymmetric 1,4-addition of boronic acids to unsaturated systems has been established. We are now applying these methods to the preparation of bioactive molecules of direct interest to GSK.<\/p>\n\n\n\n
People<\/h2>\n\n\n\n
\n
\nProf. Billy Kerr (UoS)<\/figcaption><\/figure>\n<\/div><\/div>\n\n\n\n
\nProf. John Murphy (UoS)<\/figcaption><\/figure>\n<\/div><\/div>\n\n\n\n
\nProf. Ross Denton (UoN)<\/figcaption><\/figure>\n<\/div><\/div>\n<\/div>\n\n\n\n
\n
\nProf. Simon Woodword (UoN)<\/figcaption><\/figure>\n<\/div><\/div>\n\n\n\n
\nProf. Hon Lam (UoN)<\/figcaption><\/figure>\n<\/div><\/div>\n\n\n\n
\nProf. Chris Hayes (UoN)<\/figcaption><\/figure>\n<\/div><\/div>\n<\/div>\n\n\n\n
This theme is focused on the delivery of new and efficient processes that will be directly applicable to the production of drug-like molecules. Importantly, a key design principle formulated in …<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-109","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/newmedicinesprosperitypartnership.ac.uk\/index.php?rest_route=\/wp\/v2\/pages\/109","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/newmedicinesprosperitypartnership.ac.uk\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/newmedicinesprosperitypartnership.ac.uk\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/newmedicinesprosperitypartnership.ac.uk\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/newmedicinesprosperitypartnership.ac.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=109"}],"version-history":[{"count":30,"href":"https:\/\/newmedicinesprosperitypartnership.ac.uk\/index.php?rest_route=\/wp\/v2\/pages\/109\/revisions"}],"predecessor-version":[{"id":770,"href":"https:\/\/newmedicinesprosperitypartnership.ac.uk\/index.php?rest_route=\/wp\/v2\/pages\/109\/revisions\/770"}],"wp:attachment":[{"href":"https:\/\/newmedicinesprosperitypartnership.ac.uk\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=109"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
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